Ceftriaxone injection, a third-generation cephalosporin antibiotic, is highly effective against various bacterial infections, including pneumonia, meningitis, gonorrhea, and urinary tract infections. Administered intramuscularly or intravenously, it works by inhibiting bacterial cell wall synthesis, leading to cell death. Its broad-spectrum activity covers Gram-positive and Gram-negative bacteria, with a long half-life allowing once- or twice-daily dosing. Clinical studies report cure rates of 89–99% for infections like respiratory, urinary, and central nervous system infections. Ceftriaxone injection is particularly valued for its efficacy in severe infections and surgical prophylaxis, though resistance in some bacteria, like Pseudomonas, limits its use. Side effects include diarrhea and rash.

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